Local blockade of tacrolimus promotes T-cell-mediated tumor regression in systemically immunosuppressed hostsMargaret Veitch, Kimberly Beaumont, Rebecca Pouwer, Hui Yi Chew, Ian H Frazer, H Peter Soyer, Scott Campbell, Brian W Dymock, Andrew Harvey, Terrie-Anne Cock, James W Wells
7 September 2023
ONCOS-102 plus pemetrexed and platinum chemotherapy in malignant pleural mesothelioma: a randomized phase 2 study investigating clinical outcomes and the tumor microenvironmentSantiago Ponce, Susana Cedrés, Charles Ricordel, Nicolas Isambert, Santiago Viteri, Mercedes Herrera-Juarez, Alex Martinez-Marti, Alejandro Navarro, Mathieu Lederlin, Xavier Serres, Jon Zugazagoitia, Sylvia Vetrhus, Magnus Jaderberg, Thomas Birkballe Hansen, Victor LevitskySee the full list of authors
3 September 2023
Personalized neoantigen viro-immunotherapy platform for triple-negative breast cancerRenato Brito Baleeiro, Peng Liu, Louisa S Chard Dunmall, Carmela Di Gioia, Ai Nagano, Lauren Cutmore, Jun Wang, Claude Chelala, Lydon Wainaina Nyambura, Peter Walden, Nicholas Lemoine, Yaohe Wang
16 August 2023
Functional tumor cell-intrinsic STING, not host STING, drives local and systemic antitumor immunity and therapy efficacy following cryoablationMohammad Alshebremi, Suzanne L Tomchuck, Jay T Myers, Daniel T Kingsley, Saada Eid, Muta Abiff, Melissa Bonner, Shahrazad T Saab, Sung Hee Choi, Alex Yee-Chen Huang
8 August 2023
Pattern recognition receptor agonists in pathogen vaccines mediate antitumor T-cell cross-primingMark Aleynick, Judit Svensson-Arvelund, Gvantsa Pantsulaia, Kristy Kim, Samuel A Rose, Ranjan Upadhyay, Michael Yellin, Henry Marsh, Daniel Oreper, Suchit Jhunjhunwala, Christine Carine Moussion, Miriam Merad, Brian D Brown, Joshua D Brody
24 July 2023
Combination oncolytic virus, radiation therapy, and immune checkpoint inhibitor treatment in anti-PD-1-refractory cancerSachin R Jhawar, Shang-Jui Wang, Aditya Thandoni, Praveen K Bommareddy, Jenna H Newman, Eileena F Giurini, Amanda L Marzo, Timothy M Kuzel, Vineet Gupta, Jochen Reiser, Preston Daniels, Devora Schiff, Darrion Mitchell, Nicole R LeBoeuf, Christopher SimmonsSee the full list of authors
11 July 2023
Intralesional administration of VAX014 facilitates in situ immunization and potentiates immune checkpoint blockade in immunologically cold tumorsKatherine A Reil, Shingo Tsuji, Elsa Molina, Kinsey L Nelson, Kathleen L McGuire, Matthew J Giacalone
8 June 2023
Defects in intratumoral arginine metabolism attenuate the replication and therapeutic efficacy of oncolytic myxoma virusParker Dryja, Heather D Curtsinger, Mee Y Bartee, Eric Bartee
2 June 2023
Nasal administration of recombinant Neospora caninum secreting IL-15/IL-15Rα inhibits metastatic melanoma development in lungArthur Battistoni, Louis Lantier, Anne di Tommaso, Céline Ducournau, Laurie Lajoie, Mahtab Samimi, Loïs Coënon, Clément Rivière, Mathieu Epardaud, Leslie Hertereau, Agathe Poupée-Beaugé, Juliette Rieu, Marie-Noëlle Mévélec, Gordon Scott Lee, Nathalie MoiréSee the full list of authors
16 May 2023
Macrophage-inherited exosome excise tumor immunosuppression to expedite immune-activated ferroptosisDuo Wang, Guanhua Qiu, Xiaoqi Zhu, Qin Wang, Chunyan Zhu, Chao Fang, Junjie Liu, Kun Zhang, Yan Liu
16 May 2023