Section Edited by Ignacio Melero, MD, PhD and Alexandra Snyder Charen, MD
Consisting of predictive/prognostic biomarker studies, gene expression studies in cancer immunotherapy, serological immune biomarkers, multiparameter flow cytometry-defined immune biomarkers, high content immunohistological studies, clinical trial analyses and identification of novel immune biomarkers. Manuscripts will be prioritized for peer review and publication on the basis of innovation/novelty of the biomarker-oriented research, adequate validation, clinical relevance and technological novelty.
Hsa-LINC02418/mmu-4930573I07Rik regulated by METTL3 dictates anti-PD-L1 immunotherapeutic efficacy via enhancement of Trim21-mediated PD-L1 ubiquitinationZhijia Sun, Haixing Mai, Chunyuan Xue, Zhongyi Fan, Jiangbo Li, Hairui Chen, Nan Huo, Xiaofeng Kang, Chuanhao Tang, Liaoxin Fang, Hui Zhao, Yuchen Han, Chao Sun, Huanyan Peng, Yimeng DuSee the full list of authors
1 December 2023
Targeting integrin α5 in fibroblasts potentiates colorectal cancer response to PD-L1 blockade by affecting extracellular-matrix depositionLing Lu, Yaohui Gao, Dengfeng Huang, Hu Liu, Dingzi Yin, Man Li, Jiayi Zheng, Shufei Wang, Weijun Wu, Li Zhao, Dexi Bi, Youhua Zhang, Feifei Song, Ruting Xie, Jifeng WangSee the full list of authors
1 December 2023
Evaluation of tissue- and plasma-derived tumor mutational burden (TMB) and genomic alterations of interest in CheckMate 848, a study of nivolumab combined with ipilimumab and nivolumab alone in patients with advanced or metastatic solid tumors with high TMBJie He, Natallia Kalinava, Parul Doshi, Dean C Pavlick, Lee A Albacker, Ericka M Ebot, Hanna Tukachinsky, James Pratt, Gina Fusaro, Geoffrey R Oxnard, George Green, David Fabrizio, Jonathan Baden
30 November 2023
Assessment and predictive ability of the absolute neutrophil count in peripheral blood for in vivo CAR T cells expansion and CRSMan Zhang, Xiaolu Long, Yi Xiao, Jin Jin, Caixia Chen, Jiao Meng, Wanying Liu, Aichun Liu, Liting Chen
27 November 2023
Non-invasive CT imaging biomarker to predict immunotherapy response in gastric cancer: a multicenter studyWeicai Huang, Wenjun Xiong, Lei Tang, Chuanli Chen, Qingyu Yuan, Cheng Zhang, Kangneng Zhou, Zepang Sun, Taojun Zhang, Zhen Han, Hao Feng, Xiaokun Liang, Yonghong Zhong, Haijun Deng, Lequan YuSee the full list of authors
21 November 2023
Targeting myeloid checkpoint Siglec-10 reactivates antitumor immunity and improves anti-programmed cell death 1 efficacy in gastric cancerKunpeng Lv, Mengyao Sun, Hanji Fang, Jieti Wang, Chao Lin, Hao Liu, Heng Zhang, He Li, Hongyong He, Yun Gu, Ruochen Li, Fei Shao, Jiejie Xu
7 November 2023
Multi-institutional analysis of aneuploidy and outcomes to chemoradiation and durvalumab in stage III non-small cell lung cancerJoao V Alessi, Adam Price, Allison L Richards, Biagio Ricciuti, Xinan Wang, Arielle Elkrief, Federica Pecci, Alessandro Di Federico, Malini M Gandhi, Emily S Lebow, Patricia Mae G Santos, Maria Thor, Andreas Rimner, Adam J Schoenfeld, Jamie E ChaftSee the full list of authors
1 November 2023
Comparison of SP263 and 22C3 immunohistochemistry PD-L1 assays for clinical efficacy of adjuvant atezolizumab in non-small cell lung cancer: results from the randomized phase III IMpower010 trialCaicun Zhou, Minu K Srivastava, Hao Xu, Enriqueta Felip, Heather Wakelee, Nasser Altorki, Martin Reck, Rüdiger Liersch, Anna Kryzhanivska, Satoshi Oizumi, Hiroshi Tanaka, John Hamm, Steven L McCune, Elizabeth Bennett, Barbara GitlitzSee the full list of authors
30 October 2023
Impact of Helicobacter pylori infection status on outcomes among patients with advanced gastric cancer treated with immune checkpoint inhibitorsPatrick T Magahis, Steven B Maron, Darren Cowzer, Stephanie King, Mark Schattner, Yelena Janjigian, David Faleck, Monika Laszkowska
29 October 2023
Patient-derived lymphoma spheroids integrating immune tumor microenvironment as preclinical follicular lymphoma models for personalized medicineCarla Faria, Fabien Gava, Pauline Gravelle, Juan Garcia Valero, Celia Dobaño-López, Nathalie Van Acker, Cathy Quelen, Gael Jalowicki, Renaud Morin, Cédric Rossi, Jean-Michel Lagarde, Jean-Jacques Fournié, Loïc Ysebaert, Camille Laurent, Patricia Pérez-GalánSee the full list of authors
29 October 2023