Section Edited by Ignacio Melero, MD, PhD and Alexandra Snyder Charen, MD
Consisting of predictive/prognostic biomarker studies, gene expression studies in cancer immunotherapy, serological immune biomarkers, multiparameter flow cytometry-defined immune biomarkers, high content immunohistological studies, clinical trial analyses and identification of novel immune biomarkers. Manuscripts will be prioritized for peer review and publication on the basis of innovation/novelty of the biomarker-oriented research, adequate validation, clinical relevance and technological novelty.
Real-world pan-cancer landscape of frameshift mutations and their role in predicting responses to immune checkpoint inhibitors in cancers with low tumor mutational burdenVaia Florou, Charalampos S Floudas, Asaf Maoz, Abdul Rafeh Naqash, Carter Norton, Aik Choon Tan, Ethan S Sokol, Garrett Frampton, Heloisa P Soares, Sonam Puri, Umang Swami, Breelyn Wilky, Peter Hosein, Jonathan Trent, Gilberto de Lima LopesSee the full list of authors
16 August 2023
Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastasesDavid A Schoenfeld, Myrto Moutafi, Sandra Martinez, Dijana Djureinovic, Ross D Merkin, Adebowale Adeniran, David A Braun, Sabina Signoretti, Toni K Choueiri, Fabio Parisi, Michael Hurwitz, David L Rimm, Wei Wei, Lucia Jilaveanu, Harriet M Kluger
16 August 2023
T-cell tolerant fraction as a predictor of immune-related adverse eventsJared Ostmeyer, Jason Y Park, Mitchell S von Itzstein, David Hsiehchen, Farjana Fattah, Mary Gwin, Rodrigo Catalan, Shaheen Khan, Prithvi Raj, Edward K Wakeland, Yang Xie, David E Gerber
13 August 2023
Multiple TMA-aided CRISPR/Cas13a platform for highly sensitive detection of IL-15 to predict immunotherapeutic response in nasopharyngeal carcinomaYa-Xian Wu, Shan Xing, Yu Wang, Bo-Yu Tian, Meng Wu, Xue-Ping Wang, Qi Huang, Xia He, Shu-Lin Chen, Xiao-Hui Li, Mu-Sheng Zeng, Wan-Li Liu
3 August 2023
Machine learning for prediction of immunotherapeutic outcome in non-small-cell lung cancer based on circulating cytokine signaturesFeifei Wei, Koichi Azuma, Yoshiro Nakahara, Haruhiro Saito, Norikazu Matsuo, Tomoyuki Tagami, Taku Kouro, Yuka Igarashi, Takaaki Tokito, Terufumi Kato, Tetsuro Kondo, Shuji Murakami, Ryo Usui, Hidetomo Himuro, Shun HoraguchiSee the full list of authors
11 July 2023
Intratumoral PPT1-positive macrophages determine immunosuppressive contexture and immunotherapy response in hepatocellular carcinomaJialei Weng, Shaoqing Liu, Qiang Zhou, Wenxin Xu, Minghao Xu, Dongmei Gao, Yinghao Shen, Yong Yi, Yi Shi, Qiongzhu Dong, Chenhao Zhou, Ning Ren
29 June 2023
Tobacco exposure primes the secretion of CCL21 positively associated with tertiary lymphoid structure and response to immunotherapyXuewen Yin, Hui Wang, Rutao Li, Xuming Song, Te Zhang, Yingkuan Liang, Yu-Zhong Chen, Xinnian Yu, Qixing Mao, Wenjie Xia, Bing Chen, Lin Xu, Gaochao Dong, Feng Jiang
27 June 2023
Associations of subcutaneous fat area and Systemic Immune-inflammation Index with survival in patients with advanced gastric cancer receiving dual PD-1 and HER2 blockadeMeng He, Zi-Fan Chen, Li Zhang, Xiangyu Gao, Xiaoyi Chong, Hao-shen Li, Lin Shen, Jiafu Ji, Xiaotian Zhang, Bin Dong, Zi-Yu Li, Tang Lei
22 June 2023
Method for estimation of apoptotic cell fraction of cytotherapy using in vivo fluorine-19 magnetic resonance: pilot study in a patient with head and neck carcinoma receiving tumor-infiltrating lymphocytes labeled with perfluorocarbon nanoemulsionEric T Ahrens, Brooke M Helfer, Charles F O’Hanlon, Deanne R Lister, Julie L Bykowski, Karen Messer, Benjamin I Leach, Jiawen Chen, Hongyan Xu, Gregory A Daniels, Ezra E W Cohen
19 June 2023
Early decrease of blood myeloid-derived suppressor cells during checkpoint inhibition is a favorable biomarker in metastatic melanomaAndrea Gaißler, Jonas Bochem, Janine Spreuer, Shannon Ottmann, Alexander Martens, Teresa Amaral, Nikolaus Benjamin Wagner, Manfred Claassen, Friedegund Meier, Patrick Terheyden, Claus Garbe, Thomas Eigentler, Benjamin Weide, Graham Pawelec, Kilian Wistuba-Hamprecht
7 June 2023